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The transcriptional program centered on the KEAP1-NRF2 signaling axis is one of their most critical survival mechanisms [74]

Renal impairment may lead to increased exposure of concomitant medications and/or their metabolites that are primarily renally excreted [see Drug Interactions (7.4)]

doi: 10.1111/acel.13034

Chitosan-based gastric dressing materials loaded with pomegranate peel as bioactive agents: pharmacokinetics and effects on experimentally induced gastric ulcers in rabbits